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WHAT IS METHADONE HYDROCHLORIDE?
Methadone Hydrochloride is used to treat addiction to opioids (such as heroin) as part of an approved treatment program. Methadone belongs to a class of drugs known as opioid (narcotic) analgesics. It helps prevent withdrawal symptoms caused by stopping other opioids.
Methadone may also be used to treat severe pain. Do not use methadone to relieve pain that is mild or that will go away in a few days. Methadone is not for occasional (“as needed”) use.
Dosage of Methadone Hydrochloride
Opioid-naive patients: 2.5 mg taken orally once every 8-12 hours; titrate slowly with dose increases no more frequent than every 3-5 days
Discontinue all other around-the-clock opioids
Substantial inter-patient variability, see prescribing information for guidance
Use of higher starting doses in patients who are not opioid tolerant may cause fatal respiratory depression
Patients who are opioid tolerant are those receiving, for 1 week or longer, at least 60 mg/day oral morphine, 25 mcg/hour transdermal fentanyl, 30 mg/day oral oxycodone, 8 mg/day oral hydromorphone, 25 mg/day oral oxymorphone, or an equianalgesic dose of another opioid.
WHAT ARE SIDE EFFECTS ASSOCIATED WITH USING METHADONE HYDROCHLORIDE?
Side effects of Methadone Hydrochloride include:
- Anticholinergic effects (dry mouth, palpitation, fast heart rate)
- Cardiac arrest
- Chest pain
- Feeling uneasy
- Heart attack (myocardial infarction)
- Itching and hives
- Lightheadedness or fainting
- Mental clouding or depression
- Respiratory arrest
- Respiratory/circulatory depression
- Severe cardiac arrhythmias
- Slow heart rate
- Sweating, flushing, warmness of face/neck/throat
- Urinary retention, urinating less than usual
- Visual disturbances
How Methadone come?
Methadone Hydrochloride is available in pill form as follow: 10mg and 40mg
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