Restoril (Temazepam)


Restoril (Temazepam)


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What is the Restoril (Temazepam) ?

Restoril (Temazepam) was first discovered in the 1965 and was patented by the manufacturing company. It was made available to the public during the year 1981 when the use of the drug as an anti-anxiety and anti-depression medicine was established. Over the course of time, its use and prescription level have increased gradually. Restoril (Temazepam) usually exists in the form of tablets which can be administered through oral means. High bioavailability of the drug is achieved and the metabolism of the drug takes place in the liver of the body from where it is subsequently eliminated out of the system.

Restoril (Temazepam) works by acting on the central nervous system of the body where it binds with GABA receptors to produce the favorable effects for the user. The drug is available in the market under various trade names while the most commonly used name is Restoril. The chemical formula of Temazepam is “7-Chloro-1, 3-dihydro-3-hydroxy-1-methyl-5-phenyl-1, 4-benzodiazepine-2-one” as per IUPAC. The molecular formula of the drug is C16H13ClN2O2. The molecular weight of this drug has been calculated to be 300.7 g/mol. Standard procedure for the production of the drug should be followed, in order to ensure high purity of the substance.


Restoril (temazepam) is indicated for the short-term treatment of insomnia (generally 7 to 10 days).

For patients with short-term insomnia, instructions in the prescription should indicate that Restoril™ (temazepam) should be used for short periods of time (7 to 10 days).

The clinical trials performed in support of efficacy were 2 weeks in duration with the final formal assessment of sleep latency performed at the end of treatment.


While the recommended usual adult dose is 15 mg before retiring, 7.5 mg may be sufficient for some patients, and others may need 30 mg. In transient insomnia, a 7.5 mg dose may be sufficient to improve sleep latency. In elderly or debilitated patients, it is recommended that therapy be initiated with 7.5 mg until individual responses are determined.

Short and long-term effects of Restoril (Temazepam)

There are both physical and subjective effects associated with the drug which can cause temporary and permanent issues for the patients. The short-term of the drug include medical complications which are experienced shortly after the effects of the drug start to wear off. They may include itchiness, drowsiness, dizziness, nausea and memory loss. A heavy head and physical imbalance may also be experienced by the users.

The long-term effects of the drug include withdrawal symptoms which are experienced when the user tries to relinquish the use of the drug.

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Additional information


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